Senolytic drugs boost key protective protein
Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that may protect older people against aspects of aging and a…
Using AI to predict antidepressant outcomes in youth
Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major…
Researchers review how sex steroids change gut, vaginal microbiome
It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the…
Identifying inherited gene mutations in pancreatic cancer can lead to targeted therapies, better survival
Identifying hereditary gene mutations in pancreatic cancer can help determine individualized treatments and potentially prolong survival, according to new Mayo Clinic Center for Individualized Medicine research. In the study,…
Hip decompression surgery may delay the need for implants in people with avascular necrosis
A regenerative alternative to total hip replacement delayed the need for artificial implants by at least seven years for 35% of patients who had surgery…
Regenerative technology uncovers new discoveries in liver disease
Mayo Clinic researchers have developed a method for generating bile duct cells from stem cells. This technology enables them to study important aspects of primary sclerosing cholangitis,…
Using the immune system to treat stomach cancer
An emergence of new therapies to treat stomach cancer has received FDA approval in recent years, according to Dr. Lionel Kankeu Fonkoua, a Mayo Clinic…
From fasting to a pill? Mayo Clinic scientists explore the biology of caloric restriction
New year, same topics: nutrition, healthy eating and slowing the downhill roll of aging. Eat this, not that — never that — and try this…
Large-scale exome sequencing project spots disease-fueling mutations to save lives, accelerate discoveries
Mayo Clinic is sequencing the exomes of tens of thousands of people from diverse backgrounds to investigate large-scale patterns of distinctive mutations that fuel disease.…
Long QT syndrome — Pushing the limits of gene therapy
Nearly 25 years ago, a 10-year-old boy was admitted to Mayo Clinic Children’s Center after being rescued from the bottom of a public pool. To resuscitate the…
Using AI to map zombie cells linked to disease
Mayo Clinic scientists lead the way on research into diseases of aging and their link to stressed or damaged cells that linger and cause chaos…
Comprehensive patient blood management program can reduce use of transfusions, improve patient outcomes
A growing number of hospitals have implemented patient blood management programs to reduce unnecessary blood transfusions and costs. A study published in Mayo Clinic Proceedings finds that…
Barnacles inspire development of new medical patch
Barnacles stick to pretty much anything in or near the ocean and come in more than 1,000 species. They feed using a feathery net that…
Current research into the role of the microbiome in women’s health and gynecologic cancers
The microbiome — the microorganisms that live within and on the body — plays an important role in our health, according to Dr. Marina Walther-Antonio,…
Mayo Clinic research finds immune system responds to mRNA treatment for cancer
Adding messenger RNA, or mRNA therapy, improves the response to cancer immunotherapy in patients who weren’t responding to the treatment, Mayo Clinic research shows. Immunotherapy uses the…
Mayo Clinic researchers develop algorithm to predict rheumatoid arthritis disease activity
Researchers within Mayo Clinic’s Center for Individualized Medicine and Division of Rheumatology have developed a first-of-its-kind machine learning algorithm that can predict rheumatoid arthritis disease activity in…
Promising new medical research
Discover what Mayo Clinic experts are most excited about in the field of medical research. Some new treatments may sound like sci-fi, but they’re the…
Beyond stem cells, regenerative medicine finds exosomes
Exosomes, a new tool in regenerative research, have implications for cardiac and tendon regeneration, wound healing, and incontinence, as well as many other applications. In…
Mayo Clinic Q&A: What is pharmacogenomics?
DEAR MAYO CLINIC: I’ve been hearing a lot about lab tests that can look at my genetics to see how I metabolize medications. How does this…
Study: T cells in rheumatoid arthritis have damaged mitochondria
Mayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, according to a new publication in Nature Immunology. In…
Triggering the body’s ability to heal
Erwin Kruger, M.D. — a Mayo Clinic surgeon who’s leading a Medicare claims study that uses people’s own blood to create a medical patch to…
Mayo Clinic researchers: ‘Our goal is to achieve a world without viral hepatitis’
Viral hepatitis, or inflammation of the liver, is one of the most common infectious diseases in the world. Hundreds of millions of people live with…
A new, shorter treatment for HPV-associated oral cancer
Mayo Clinic researchers have found that a new, shorter treatment for patients with HPV-associated oropharynx cancer leads to excellent disease control and fewer side effects,…
Bad fat, misbehaving kidneys may share common offender
In a recent paper published in Cell Reports, Mayo Clinic scientists found that a sensory device on cells determines if a fat cell burns fat or…
Winter, holidays and keeping safe from COVID-19 and other viruses
As the end of the year approaches, it’s only the beginning of the season for illnesses like the cold and flu. Add COVID-19 and other viruses to the list,…
COVID Conversations: Experts urge COVID-19 boosters to fight omicron surge
In a podcast recorded for the Mayo Clinic News Network, Gregory Poland, M.D., discuses the latest information on COVID-19 variants and shares advice on how…
Mayo Clinic Q and A: Knee reconstruction in younger patients
DEAR MAYO CLINIC: I am 35 and have had various knee issues for a few years. I’m a runner and played other sports. My primary care…
Biological age and other AI tools in preventive cardiology
Doctors have observed for many years that people age at different speeds, according to Dr. Francisco Lopez-Jimenez, chair of preventive cardiology at Mayo Clinic in…
Mayo Clinic Q&A podcast: Post COVID-19 syndrome can be a long haul
Most people who have COVID-19 recover completely within a few weeks. But some people — even those who had mild versions of the disease —…
Testing for COVID-19 at home
The emergence of a new COVID-19 variant, omicron, has heightened safety protocols and plans to help people stay safe from illness as researchers and experts learn more about…
HIV research provided foundation for COVID-19 research
This year’s World AIDS Day will be commemorated on Dec. 1. It was 40 years ago in June that the first scientific report was made describing pneumocystis pneumonia, which later…
Mayo Clinic Q&A podcast: Boosters reduce vulnerability to COVID-19 variants
Omicron, a new COVID-19 variant of concern, has been detected in all regions of the world, including North America. While research and clinical observations on the new…
COVID-19 pill gets advisory panel approval
The first oral antiviral medication to treat COVID-19 is one step closer. A Food and Drug Administration (FDA) advisory panel has voted to recommend emergency use authorization…
The dawning of regenerative neurosurgery
Regenerative neurosurgery is poised to transform care of neurological disorders that previously had little hope for improvement, according to a Mayo Clinic review published in The BMJ. Healing…
A robotic GPS for targeting, delivering regenerative biotherapies
A remote-controlled bronchoscope that acts like a GPS system hunts down hard to find lung masses and accurately biopsies them, according to a Mayo Clinic…
Colorectal cancer screening aims younger: 45 is the new 50
Millions of people who thought colorectal cancer screening was somewhere off in their distant future recently got a wake-up call. The recommended age for taking…
Fruit flies help Mayo Clinic researchers look for ways to protect nerve cells from chemotherapy
Fishing them out of a drink, you may not see the benefit of fruit flies. But they are a vital scientific model, and at Mayo…
How clinical trials work: COVID-19 and beyond
Clinical trials follow rigorous scientific processes that usually take many years to complete. However, during the COVID-19 pandemic, clinical trials are operating on fast-forward. In…
What’s new in regenerative medicine research for neurodegenerative diseases
The cells in the brain and spinal cord don’t replace themselves after they’ve been injured, such as from a neurodegenerative disease like Parkinson’s, or as…
The innovative research behind HIV/AIDS treatment
It’s been 40 years since the release of the first scientific report describing acquired immune deficiency syndrome (AIDS). Thanks to innovative research, scientists learned how…
Fatigue that won’t stop: COVID-19 long-hauler syndrome
Experts estimate that 10 percent to 30 percent of people who have had COVID-19 experience fatigue and other symptoms many months after initial infection. In…
Study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.…
Instigator gene associated with Alzheimer’s disease identified
In a new paper published in Nature Communications, Mayo Clinic researchers and collaborators report the protein-coding gene SERPINA5 may worsen tau protein tangles, which are…
Study finds lung transplant patients given antifungal preventive drugs have lower risk of death
Antifungal preventive medications reduce mortality risk by half in the first year following lung transplantation, according to Mayo Clinic research involving 667 patients who received…