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Mayo Clinic on Alzheimer's Disease and Other Dementias

A guide for people with dementia and those who care for them

Jonathan Graff-Radford, M.D. and Angela M. Lunde, M.A.

  • The current number of people worldwide living with dementia is estimated to be 50 million, and could be nearly 150 million by 2050.
  • The total number of new cases of dementia each year worldwide is nearly 10 million, implying one new case every three seconds.
  • The cost of health care for those with dementia in the United States is $818 billion, and will continue to increase as the population ages.



Dementia is a serious health challenge, and by some estimates the number of people living with dementia could triple by 2050. While Alzheimer’s disease is the most common type of dementia, many related types of dementia also affect adults worldwide, causing loss of cognitive functions such as memory, reason and judgment. Although the diseases that cause dementia have long been considered unrelenting and incurable, recent advances offer hope.

Are there ways you can lower your risk of dementia? Can it be prevented? Can you live well with dementia? If so, how? Mayo Clinic on Alzheimer’s Disease and Other Dementias provides answers to these important questions and more.

2020 • 414 pages • Mayo Clinic Press

Ronald C. Petersen, Ph.D., M.D.Jonathan, Graff-Radford, M.D.Jonathan, Graff-Radford, M.D.

Dr. Graff-Radford,  is a behavioral neurologist at Mayo Clinic in Rochester, Minn., where he evaluates and treats patients with cognitive disorders, including dementa. An associate professor of neurology at Mayo Clinic College of Medicine and Science, Dr. Graff-Radford also serves as a co-investigator in the Mayo Clinic Alzheimer's Disease Research Center and the Mayo Clinic Study of Aging.

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Angela M. Lunde, M.A.

Angela M. Lunde, M.A., has worked in dementia care for nearly 20 years. She is a co-investigator of the Outreach, Recruitment and Education Core in the Mayo Clinic Alzheimer's Disease Research Center, where she focuses on the emotional well-being and quality of life of those living with dementia and their care partners.

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