
Ticks are found in every U.S. state, and different tick-borne illnesses are found in different parts of the country. Lyme — which is caused by four main species of bacteria — is the most common tick-borne disease. But ticks carry many other pathogens that can cause disease. In this Answers…

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Research & Innovation
Nanopore sequencing method rapidly detects, identifies antibiotic-resistant microbes, Mayo Clinic research shows
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A growing number of people are dying from antibiotic-resistant infections. These infections are fueled by microbial species that are mutating to evade the drugs developed to destroy them. More than 1.2 million people worldwide died in 2019 from antibiotic-resistant infections. In response, a team of researchers from …

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Research & Innovation
A breakthrough in distinguishing benign adrenal tumors from cancerous ones
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Approximately 80 million CT scans are performed in the United States every year. Adrenal tumors are found incidentally in about 5% of these scans. Most of these tumors will turn out to be benign, but a small fraction will be adrenal cortical carcinoma, a type of cancer with high mortality and frequent…

Medical teams at Mayo Clinic can use radiology images to create 3D models that are life size and specific to each patient. The 3D models help give patients a better understanding of what will happen during a procedure and the risks involved, which improves communication with their doctors. For surgeons,…

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Research & Innovation
Plasma biomarker screening could improve accuracy, health equity in Alzheimer’s disease diagnosis
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Mayo Clinic researchers have identified a new set of molecular markers in blood plasma. This discovery could lead to the development of improved diagnostic tests for Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia, affecting 6.2 million people in the U.S. The Mayo Clinic study, published in eBioMedicine, is…

New research from Mayo Clinic shows that lack of sufficient sleep combined with free access to food increases calorie consumption and consequently fat accumulation, especially unhealthy fat inside the belly. Findings from a randomized controlled crossover study led by Naima Covassin, Ph.D., a cardiovascular medicine researcher at Mayo Clinic, show that lack…

Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that may protect older people against aspects of aging and a range of diseases. Their findings, which are published in eBioMedicine demonstrate this in mice and human studies. Senolytics developed at Mayo Clinic and given once clear…

Mayo Clinic researchers have taken the first step in using artificial intelligence (AI) to predict early outcomes with antidepressants in children and adolescents with major depressive disorder, in a study published in The Journal of Child Psychology and Psychiatry. This work resulted from a collaborative effort between the departments of…

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Research & Innovation
Researchers review how sex steroids change gut, vaginal microbiome
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It is well-established that the human body’s microbiome ― the bacteria in the gut ― dramatically affects health and disease. However, the role of the gut in women’s health outcomes is largely unknown. Mayo Clinic and Wellesley College researchers focused on how the interactions of steroids on gut and vaginal…

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Research & Innovation
Identifying inherited gene mutations in pancreatic cancer can lead to targeted therapies, better survival
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Identifying hereditary gene mutations in pancreatic cancer can help determine individualized treatments and potentially prolong survival, according to new Mayo Clinic Center for Individualized Medicine research. In the study, which was published in Clinical and Translational Gastroenterology, nearly 1 in 6 people diagnosed with pancreatic cancer were found to have an inherited cancer-related gene…

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Research & Innovation
Hip decompression surgery may delay the need for implants in people with avascular necrosis
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A regenerative alternative to total hip replacement delayed the need for artificial implants by at least seven years for 35% of patients who had surgery to treat avascular necrosis. That condition occurs when blood flow to the hip joint known as the femoral head is constricted, causing bone cells to die.

Mayo Clinic researchers have developed a method for generating bile duct cells from stem cells. This technology enables them to study important aspects of primary sclerosing cholangitis, a rare bile duct disease that often destroys the liver. Using these regenerative technologies, Robert Huebert, M.D., and Nidhi Jalan Sakrikar, Ph.D., also confirmed that primary sclerosing…
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